Yes, this would be possible. You would need to add multiple WHERE clause conditions, using the same pattern for each. However, when you specify the SELECT clause through the Specify a Selected Statement screen of the SqlDataSource wizard, the WHERE clause filter expressions specified are joined by ANDs. That is, if you followed the steps outlined earlier in this hour and added three filter expressions to the Title, Author, and Genre columns using the LIKE operator with a parameter value based on the titleSearch TextBox, the resulting SELECT query would be
SELECT *
FROM [Books]
WHERE ([Title] LIKE '%' + @Title + '%') AND
([Author] LIKE '%' + @Author + '%') AND
([Genre] LIKE '%' + @Genre + '%')